Cancer Genes Causing

Cancer
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Cancer is by itself a disease of cells or disease where the growth of cells is uncontrollable. Most groups of genes causing cancer are:
Tumor suppressor genes, they are protective genes by limiting the growth, and as tumor suppressor mutates, cells do grow uncontrollably thus forming a tumor, and examples of such genes are p53, BRCA1. Oncogenes, they change healthy cells into a cancerous cell, such genes are HER2 and the RAS family. Also, the DNA repair genes, these do fix mistakes that are made while DNA is being copied, they include BRCA2. Mutation in cancer includes an acquired mutation in which it occurs during damage to genes in a specific cell while gremlin mutations do occur in sperm or egg cell. It is inherited cancer. Also, point mutation resulting in a change in one base in the DNA sequence. There is Copy number variation (CNV) in which chunks of the DNA are repeated, inserted or lost.
HER2 (human epidermal growth factor receptor 2)
In most healthy breast cell HER2 do perform the function for growing more cells and repairing the damaged ones. It is a gene which creates HER2 proteins. HER2 is a gene that do mostly play a role in the development of breast cancer (Miller et al, 1981). These genes do make HER2 proteins which are receptors on the breast cells. When HER2 genes do not function in the right manner and multiplies (HER2 gene amplification), this results in reaction of the breast cells by making HER2 receptors thus the breast cells growing and dividing in an uncontrollable rate, leading to breast cancer.

In regards with RAS family of genes, this makes proteins that are involved in the cell communication pathways, cell death and cell growth.
Cancer resulting from excess receptors is referred to as HER2 positive. This type of cancer is not inherited at all. Instead, it is considered to be a somatic genetic mutation.
Studying the biology of cancer cells.
In research, we begin by comparing the genes found in DNA and the growth in a pattern of cancer cells to that of healthy cells. In this case, we consider a situation of this kind of experiment, does the use of Aloe Vera plant extracts cure to breast cancer? The methodology of molecular-based techniques should be used on testing. The researcher should acquire the extracts, have a different combination of females from different places.
Independent variable, the women involved are either in research or not.
The dependent variable, reaction to the drug and body adjustment was a reasonable cure.
Controlled variables same duration of time, the same women involved and same environment as well as food
To conclude on, it’s quite important to note that cancer being a genetic disease and thus most mutations that occur in genes of cancer cell are as a result of exposure to environmental factors which are very controllable. This includes eating fresh vegetables and fruits, quitting smoking and doing exercise amongst others.

Reference
Miller, A. B., Hoogstraten, B. F. A. U., Staquet, M. F. A. U., & Winkler, A. (1981). Reporting results of cancer treatment. cancer, 47(1), 207-214.