The Toxic Relationship Between Sugar And Brain

The toxic relationship between sugar and brain

There is a direct relationship between brain and sugar consumption. In the article “The Neuroscience of Sugars in Taste, Gut-Reward, Feeding Circuit, and Obesity” the mechanisms involved in the choice of sugar consumption are addressed, which are included in three main components;The brain, intestine and tongue (through the perception of flavor) the latter is carried out through type 1 taste receptors (T1R2) and 2 (T1R3) in which the sucralous, glucose and fructose is joined and are located and are locatedIn the 1p36 chromosome region in the human.  In addition, it is explained how the excessive consumption of this sweet substance decreases the perception of flavor due to a diminished activity of sweetness sensitive to sweetness. This in turn are mediated by the increase in the activity of the n-acetyl glycosamine sensor transferase linked to O and thereby decreases the effectiveness of physiological circuits that help avoid reaching obesity. Since it causes a lack of control when the amounts of sugar consumption increasing because as mentioned, the perception of sweet taste is lost (more quantity is needed to feel the taste), diseases are generated. For example, the obesity that alone causes damage to health, but more diseases are also derived from it that will cause more adverse effects. It is specified that the consumption of sugary drinks is closely related to type 2 diabetes mellitus and this consumption of carbohydrates is greater when it occurs in its liquid state as in sugary drinks since they go unnoticed.

Addiction behaviors are developed due to the consumption of high foods in simple carbohydrates and food with high palatability liking the palate as they are consumed more frequently .

Another study declared that the RNA of the vasopressin gene 1 improved its expression with alcohol consumption especially in adolescent women, ‘’ [..] These data show that behavioral and neuronal alterations that can serve as risk factors in subsequent drug vulnerabilities ’’ ’. This last statement put in the article emphasizes how the gene is closely related to addiction behaviors. Vasopressins are defined as ‘’ antidiuretic octopeptide hormones released by neurohypophysis of all vertebrates (chemical composition varies with the species). They control metabolism and water balance, regulating the lung, gills, kidney, etc. And the loss of water, and also contract the smooth muscles. They can also be neurotransmitters. They also include synthetic derivatives of vasopressin. Vasopressins are used pharmacologically as renal agents, vasoconstrictor and hemostatic agents.’’

Diabetes mellitus occurs when the body does not produce enough insulin or does not use it as it should. High blood glucose levels, during pregnancy for example, can cause a cellular class, which will determine gene expression to develop DM2.  As medical treatment for diabetes there are different drugs (insulin) and are available in different presentations according to patient’s needs. One of them is metformin is used as hypoglycemic, in addition to preventing cardiovascular events and decreased triglycerids and cholesterol, which are diseases that usually accompany diabetes. As adverse effects, gastrointestinal problems, nausea, vomiting, among others can occur, among others. 

A study was carried out to 250 families in which there was more than one child with diabetes mellitus and evidence was found that a locus location of an IDDM susceptibility gene near D15S107 on the 15Q26M chromosome, where there is association in presenting this Gen and suffer diabetes mellitus. 

DM2 has as a sequel a disease called diabetic neuropathy, it is defined as ‘’ peripheral nerve disorder caused by diabetes or poor blood sugar control ’. This tells us that as the progression of this sequel, the muscles, organs, tissues, sphincters, will stop working, since it is the peripheral nerves who handle all the function of the body.  Although carbohydrates are an important element in the body and especially the brain for proper functioning, the difference between the consumption of simple sugars and that from natural foods should be taken into account since simple sugars and artificial sweeteners, without satanizing any of these energy sources.

Now, you can get to the idea that the gene expressed highly for the neurotransmitter vasopressin could have something to do with addiction behavior also to sugars, and exactly the opposite happens in what is the diabetes insipid neurohypophysiary;where there is a defective expression of the gene that encodes for the vasopressin and therefore for the gene that encodes the expression of its receiver. Then, it could be concluded that, the more expression of the vasopressin gene, the more sugar addiction there is and the more risk of suffering DM2. The less expression of the same, the more likely.

On the other hand, the gene of the Vasopressin 1a receptor is related to trust and reciprocity, with this we could reach the idea that falling in love or the simple fact of wanting someone has to do with this gene, because when this falling in love exists byYou have a behavior of trust and feeling of returning affection to the other person.

Finally, relating and integrating, we conclude that there may be a relationship between addictions in terms of love relationships and HC intake, all in order and thanks to the expression of the vasopressin gene.

Bibliographic references

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